Fluconazole is used to treat and prevent fungal and yeast infections. It belongs to a class of medications known as azole antifungals. It works by inhibiting the growth of specific types of fungus. Before you begin taking fluconazole, and each time you get a refill, read the Patient Information Leaflet provided by your pharmacist. If you have any concerns, consult your doctor or pharmacist. As directed by your doctor, take this medication by mouth with or without food once daily.