Advil cold and sinus is the combination of an NSAID (nonsteroidal anti-inflammatory drug) Ibuprofen and the decongestant Pseudoephedrine. Is used to treat nasal and/or sinus congestion, pain, headache, cough, and fever caused by the common cold. Do not use Ibuprofen for long periods, if you have a history of severe CAD (coronary artery disease) or right before or after heart surgery, peptic ulcer, rectal bleeding, nasal polyps, acute renal insufficiency, anticoagulant, allergy to aspirin, acute neurologic deficit if you have used any MAO inhibitor in the past 14 days, in a child under 4 years of age and/or if you are in your 3rd trimester of pregnancy. Never take dosages greater than 800mg or a total daily dose greater than 3200mg. Concomitant use of alcohol may increase the risk of bleeding. Mild side effects may be experienced like gastric discomfort, heartburn, and nausea.